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Core issues in human evolution and population genetics. Molecular evidence for the origin of modern humans, reconstruction of human migrations, race, and detection of admixture between populations. Implications for human disease. Offered on a graded basis only. Prerequisite or corequisite: BSCI 1100, BSCI 1105, or BSCI 1510. [3]

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(Also listed as BSCI 2105) Evolutionary theory, with emphasis on evolutionary mechanisms. Microevolutionary processes of adaptation and speciation and macro-evolutionary patterns. Evidence from genetics, ecology, molecular biology, and paleontology in the historical context of the neo-Darwinian synthesis. No credit for students who have earned credit for BSCI 2105. Not open to students who have completed BSCI 5205.

(Also listed as BSCI 2138) Population biology, evolutionary ecology, community structure, with emphasis on species interactions, including competition, predation, and symbiosis. No credit for students who have earned credit for BSCI 2138, 2238, or 5238. [3]

Macroevolutionary processes as observed through the fossil record. Inference of evolutionary relationships, physiology, reproduction, behavior, and ecology. Fundamentals of paleobiology, paleoecology, paleoclimates, macroecology, biogeography, geology, geochemistry, anthropology, and conservation paleobiology. Effects of climate change and human impacts, in deep-time. [3]

(Also listed as BSCI 3233) Ecological, evolutionary, social, and economic aspects of biodiversity loss and ecosystem disruption due to human activities. Climate change, habitat fragmentation, species overexploitation, and invasive species. Sustainable development, habitat restoration, and species reintroduction. [3]

(Also listed as BSCI 3242) Application of evolutionary principles to biomedical issues to understand and improve human health. Aging, antibiotic resistance, defenses, cardiovascular disease, and cancer. Interdisciplinary evidence from anthropology, genetics, ecology, immunology, and molecular biology. No credit for students who have earned credit for 3242. [3]

(Also listed as 3240) Molecular evolution of adaptation and disease. Molecular mechanisms of human disease approached through analysis of evolutionary adaptation in extremophile animals. Comparative analysis of multiple protein systems that facilitate adaptation in some species but are implicated in human conditions such as cancer, visual impairment, and aging. Not open to students who completed BSCI 3890/5890 section 02 offered spring 2024. No credit for students who have earned credit for BSCI 3240. [3]

(Also listed as BSCI 3272) Aims and importance of the science. Retrieval of genome data from public databases; experimental and computational methods used in analysis of genome data and their annotation. Functional aspects of genomics, transcriptomics, and proteomics; use of phylogenetics and population genomics to infer evolutionary relationships and mechanisms of genome evolution. No credit for students who have earned credit for 3272. [3]

Literature-guided study of pioneering research in biological sciences. Principles of evolution, ecology and organismal biology, genome architecture and information flow, cell organization, protein structure and function, and neurobiology and behavior. [4]

(Formerly listed as 5268) (Also listed as 4268) Principles of infectious disease ecology, epidemiology, and evolution. Host-parasite coevolution, parasite ecology, and the evolution of resistance, tolerance, and pathogen virulence in humans, other animals, and plants. Experimental and mathematical approaches. Serves as repeat credit for students who have earned credit for BSCI 5890-04 offered fall 2023 or fall 2022. No credit for students who have earned credit for BSCI 3268 offered prior to Fall 2025 or BSCI 4268 offered Fall 2025 forward. [3]

Weekly discussions lead by faculty, postdocs, and enrolled students in evolutionary studies fields. Contact Dr. Paul Durst for permission. Common name is Journal Club [1]

This course introduces students to the field of Cancer Systems Biology, which aims to frame cancer as a complex biological system through multidisciplinary approaches linking biology, engineering, and computer science. It is designed to teach students how to apply "systems thinking" to the analysis and modeling of fundamental questions in cancer research. The course will provide an overview of basic concepts in systems biology, including complexity, systems dynamics, networks, evolution and game theory. A survey of mathematical, statistical and computational tools will empower students to apply these concepts to concrete cancer biology projects. Examples of class activities include: construction of gene or signaling networks using literature- based knowledge and existing databases; visualization of multidimensional data; and, basic programming workshops. There will be strong emphasis on designing "systems" experiments and interpreting results in a modern cancer research laboratory. [3] Tyson

(Also listed as EES 3220) Ecology, classification, and evolution of important groups of fossils, emphasizing invertebrates. Change in marine ecosystems through geologic time. Causes and effects of rapid evolution events and mass extinctions. Three hours of lecture and one laboratory period per week. No credit for students who have earned credit for 3220 or 3220W. [4]

Integration of evolutionary biology, paleobiology, ecology, and biogeography to understand interactions between organisms and their environments over large spatial and temporal scales, including in ancient ecosystems. The discipline of macroecology; nature of species, niches, and communities; abundance and distribution of species; species diversity; composition and assembly of continental biotas; allometry and body size; evolutionary dynamics; methodological advances. [3]

Evolutionary processes that operate on geological time scales. Evolutionary theory; systematics; speciation and extinction; evolutionary benefits of sexual reproduction; co-evolution; convergence; biogeography; and relevance of evolution to modern ecology and conservation. Effects of abiotic processes on the evolution of terrestrial and marine organisms. [3]

(Also listed as Molecular Physiology and Biophysics 8341) This course will cover the statistical, population, and analytical aspects of modern human genetics research. Topics to be covered include human population genetics, quantitative genetics, disease gene discovery (emphasizing design, statistical and molecular techniques), linkage and association analyses, computational genetics, and evolutionary genetics. Clinical examples, subject ascertainment, and study design will also be emphasized. Students must have a strong understanding of Mendelian genetics and basic biostatistics. Prerequisite: consent of instructor. SPRING. [4]